Pharmaceutical Evaluation of Commercial Corticosteroid Ointments and Creams

[Evaluation of the permeability of corticosteroid in hairless mouse and hairless micropig skin from admixture of commercially available corticosteroid ointments and/or creams].

Yucatan hairless micropig (YHMP) skin has been shown to have histology and physiologic properties similar to human skin. To assess the relationship between the permeability of corticosteroid ointments and five types of commonly used admixtures of corticosteroid through hairless mice (HM) or YHMP skin and the clinical effects in humans, we conduct by in vitro experiments using HM and YHMP skin. ...

Survey of mixing commercially available corticosteroid ointments with other ointments and the anti-inflammatory activity of the admixtures.

We surveyed the prescriptions from the Department of Dermatology in a city hospital to determine the status of the use of admixtures of corticosteroid ointments with other ointments. Thirty percent of the prescriptions of topical ointment therapy for outpatients of the Department were for admixture ointments. They were prescribed for patients aged 2 months to over 90 years. The mixing ratios of...

Characterization and stability study of some pharmaceutical ointments

In the present study we have determined some characteristics (aspect, odor, solubility, emulsion type, water and volatile substances content, total fatty matter, saponification index, ester index) for three pharmaceutical ointments belonging to the group of non-steroidal anti-inflammatory: Diclac, Ketonal, Indometacin and one antibiotic ointment for ophthalmic use: Ophtagram. In order to achiev...

Barrier creams and their evaluation.

Contact dermatitis caused by pharmaceutical ointments containing 'ozonated' olive oil.

Olive oil is a mixture of several glycerides of (mainly) oleic acid, but also palmitic, linoleic, stearic and arachidic acids, and also contains squalene, phytosterol, tocopherol and phenolic compounds. It is considered to be a weak irritant and a low-risk sensitizer (1), with the actual allergen(s) being unknown. Apart from its culinary use and its presence in cosmetics, itmayalso beused in to...